BDBM50222737 CHEMBL238587::cyclo(-L-Am7(S2Py)-Aib-L-Ala-D-Tic-)

SMILES C[C@H]1CN2Cc3ccccc3C[C@@H]2C(=O)N[C@@H](CCCCCSSc2ccccn2)C(=O)NC(C)(C)C(=O)N1

InChI Key InChIKey=ALYDIERJMKHYLO-NKKJXINNSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222737   

TargetHistone deacetylase 6(Mus musculus)
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222737(CHEMBL238587 | cyclo(-L-Am7(S2Py)-Aib-L-Ala-D-Tic-...)
Affinity DataIC50:  29nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222737(CHEMBL238587 | cyclo(-L-Am7(S2Py)-Aib-L-Ala-D-Tic-...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222737(CHEMBL238587 | cyclo(-L-Am7(S2Py)-Aib-L-Ala-D-Tic-...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed