BDBM50222738 CHEMBL391383::cyclo(-L-Am7(S2Py)-Aib-L-Ph4-D-Pro-)

SMILES CC1(C)NC(=O)[C@H](CCCCCSSc2ccccn2)NC(=O)[C@H]2CCCN2C(=O)[C@H](CCc2ccccc2)NC1=O

InChI Key InChIKey=VOORCQROXYSHCG-CCDWMCETSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222738   

TargetHistone deacetylase 6(Mus musculus)
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222738(CHEMBL391383 | cyclo(-L-Am7(S2Py)-Aib-L-Ph4-D-Pro-...)
Affinity DataIC50:  36nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222738(CHEMBL391383 | cyclo(-L-Am7(S2Py)-Aib-L-Ph4-D-Pro-...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222738(CHEMBL391383 | cyclo(-L-Am7(S2Py)-Aib-L-Ph4-D-Pro-...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of human HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed