BDBM50225505 CHEMBL358641::ICI-58301

SMILES CCCc1nc(C)cn2c(NC(C)=O)nnc12

InChI Key InChIKey=QXRRTQNLNYMWKD-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50225505   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50225505(CHEMBL358641 | ICI-58301)Copy SMILESCopy InChI

Affinity DataKi:  2.17E+5nMAssay Description:Binding affinity for low Km cAMP phosphodiesterase PDE II of sheep lungMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50225505(CHEMBL358641 | ICI-58301)Copy SMILESCopy InChI

Affinity DataKi:  7.17E+5nMAssay Description:Binding affinity for [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of sheep lungMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI