BDBM50229653 (S)-tetrahydrofuran-3-yl 4-((4-(3,5-dimethylphenyl)piperidin-1-ylsulfonyl)methyl)-4-(hydroxycarbamoyl)piperidine-1-carboxylate::CHEMBL254510

SMILES Cc1cc(C)cc(c1)C1CCN(CC1)S(=O)(=O)CC1(CCN(CC1)C(=O)O[C@H]1CCOC1)C(=O)NO

InChI Key InChIKey=ANOPQMHOFNTJCB-QFIPXVFZSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50229653   

LigandPNGBDBM50229653((S)-tetrahydrofuran-3-yl 4-((4-(3,5-dimethylphenyl...)
Affinity DataIC50:  833nMAssay Description:Inhibition of HER2 sheddase in human BT474 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50229653((S)-tetrahydrofuran-3-yl 4-((4-(3,5-dimethylphenyl...)
Affinity DataIC50:  955nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50229653((S)-tetrahydrofuran-3-yl 4-((4-(3,5-dimethylphenyl...)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50229653((S)-tetrahydrofuran-3-yl 4-((4-(3,5-dimethylphenyl...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50229653((S)-tetrahydrofuran-3-yl 4-((4-(3,5-dimethylphenyl...)
Affinity DataIC50:  286nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50229653((S)-tetrahydrofuran-3-yl 4-((4-(3,5-dimethylphenyl...)
Affinity DataIC50:  315nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed