BDBM50230 (E)-3-(4-chloranyl-3-nitro-phenyl)-N-(4-pyrrolidin-1-ylphenyl)prop-2-enamide::(E)-3-(4-chloro-3-nitro-phenyl)-N-(4-pyrrolidinophenyl)acrylamide::(E)-3-(4-chloro-3-nitrophenyl)-N-(4-pyrrolidin-1-ylphenyl)prop-2-enamide::(E)-3-(4-chloro-3-nitrophenyl)-N-[4-(1-pyrrolidinyl)phenyl]-2-propenamide::3-(4-chloro-3-nitrophenyl)-N-[4-(1-pyrrolidinyl)phenyl]acrylamide::MLS000574740::SMR000196170::cid_1332381

SMILES [O-][N+](=O)c1cc(\C=C\C(=O)Nc2ccc(cc2)N2CCCC2)ccc1Cl

InChI Key InChIKey=AYMYBVLHBKEGED-ONNFQVAWSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50230   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50230((E)-3-(4-chloranyl-3-nitro-phenyl)-N-(4-pyrrolidin...)
Affinity DataIC50:  5.40E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
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TargetDNA repair protein RAD51 homolog 1(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM50230((E)-3-(4-chloranyl-3-nitro-phenyl)-N-(4-pyrrolidin...)
Affinity DataIC50:  5.30E+4nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
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TargetCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50230((E)-3-(4-chloranyl-3-nitro-phenyl)-N-(4-pyrrolidin...)
Affinity DataIC50:  3.29E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50230((E)-3-(4-chloranyl-3-nitro-phenyl)-N-(4-pyrrolidin...)
Affinity DataIC50:  1.09E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50230((E)-3-(4-chloranyl-3-nitro-phenyl)-N-(4-pyrrolidin...)
Affinity DataIC50:  2.09E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay