BDBM50230573 CHEMBL4068337

SMILES FC(F)(F)C1(N=C(Nc2c1c(=O)[nH]c(=O)n2Cc1ccccc1)c1cccs1)C(F)(F)F

InChI Key InChIKey=HOCOKOKYRFWIAT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50230573   

TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50230573(CHEMBL4068337)
Affinity DataIC50:  1.50E+3nMAssay Description:Antagonist activity at human GLP-1R expressed in TREx293 cells co-expressing cAMP sensitive luciferase assessed as inhibition of exendin-4-induced cA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50230573(CHEMBL4068337)
Affinity DataIC50:  1.29E+3nMAssay Description:Antagonist activity at human GLP-1R expressed in TREx293 cells co-expressing cAMP sensitive luciferase assessed as inhibition of GLP1 (7 to 36 residu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50230573(CHEMBL4068337)
Affinity DataIC50:  1.30E+3nMAssay Description:Antagonist activity at human GLP-1R expressed in TREx293 cells co-expressing cAMP sensitive luciferase assessed as inhibition of GLP1 (7 to 36 residu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50230573(CHEMBL4068337)
Affinity DataIC50:  1.51E+3nMAssay Description:Antagonist activity at human GLP-1R expressed in TREx293 cells co-expressing cAMP sensitive luciferase assessed as inhibition of exendin-4-induced cA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed