BDBM50230574 CHEMBL4103452

SMILES COc1cccc(c1)C1=NC(c2c(N1)n(CC(C)C)c(=O)[nH]c2=O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=WUSQUKNNIKUUSM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50230574   

TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50230574(CHEMBL4103452)
Affinity DataIC50:  7.20E+3nMAssay Description:Antagonist activity at human GLP-1R expressed in TREx293 cells co-expressing cAMP sensitive luciferase assessed as inhibition of exendin-4-induced cA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50230574(CHEMBL4103452)
Affinity DataIC50:  7.20E+3nMAssay Description:Antagonist activity at human GLP-1R expressed in TREx293 cells co-expressing cAMP sensitive luciferase assessed as inhibition of GLP1 (7 to 36 residu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50230574(CHEMBL4103452)
Affinity DataIC50:  7.24E+3nMAssay Description:Antagonist activity at human GLP-1R expressed in TREx293 cells co-expressing cAMP sensitive luciferase assessed as inhibition of exendin-4-induced cA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50230574(CHEMBL4103452)
Affinity DataIC50:  7.24E+3nMAssay Description:Antagonist activity at human GLP-1R expressed in TREx293 cells co-expressing cAMP sensitive luciferase assessed as inhibition of GLP1 (7 to 36 residu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed