BDBM50231059 CHEMBL252785::N-(2-(5-hydroxy-1H-indol-3-yl)propyl)-4-(trifluoromethoxy)benzamide

SMILES CC(CNC(=O)c1ccc(OC(F)(F)F)cc1)c1c[nH]c2ccc(O)cc12

InChI Key InChIKey=AUYHTGSUOKGCJD-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231059   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50231059(CHEMBL252785 | N-(2-(5-hydroxy-1H-indol-3-yl)propy...)Copy SMILESCopy InChI

Affinity DataIC50:  550nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced calcium influx in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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