BDBM50232325 CHEMBL4074782

SMILES Cc1ccccc1-c1nnc(Cc2nc3ccccc3[nH]2)o1

InChI Key InChIKey=XIEDBRMNHVILCQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232325   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232325(CHEMBL4074782)
Affinity DataIC50:  4.68E+4nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232325(CHEMBL4074782)
Affinity DataIC50:  3.97E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232325(CHEMBL4074782)
Affinity DataIC50:  3.97E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed