BDBM50232330 CHEMBL4068254

SMILES C(c1nc2ccccc2[nH]1)c1nnc(o1)-c1ccccc1

InChI Key InChIKey=HDKMMBRKVCIVNF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232330   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232330(CHEMBL4068254)
Affinity DataIC50:  3.18E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232330(CHEMBL4068254)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232330(CHEMBL4068254)
Affinity DataIC50:  3.18E+4nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed