BDBM50232683 CHEMBL4066086

SMILES COc1cc(CN)ccn1

InChI Key InChIKey=UQAHBOKPZNLKRF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50232683   

TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232683(CHEMBL4066086)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232683(CHEMBL4066086)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-lysine 6-oxidase(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50232683(CHEMBL4066086)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human LOX expressed in HEK cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232683(CHEMBL4066086)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

Curated by ChEMBL
LigandPNGBDBM50232683(CHEMBL4066086)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed