BDBM50233155 CHEMBL4080953::US11124490, Compound 28b
SMILES CN1CCN(CC1)S(=O)(=O)c1cc(C(=O)Nc2cc(Cl)c(F)c(Cl)c2)c(Cl)cc1Cl
InChI Key InChIKey=WGYCFEGHYBMUIA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50233155
Affinity DataIC50: 55.5nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Tennessee Health Science Center
Curated by ChEMBL
University Of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of ATX (unknown origin) expressed in human A2058 cells assessed as inhibition of LPC-induced cell invasion after 20 hrs by calcein-AM dye ...More data for this Ligand-Target Pair