BDBM50233164 CHEMBL4105201::US11124490, Compound 29

SMILES CN1CCN(CC1)S(=O)(=O)c1cc(C(=S)Nc2cc(Cl)c(F)c(Cl)c2)c(Cl)cc1Cl

InChI Key InChIKey=AQXJRHLJOZUMTK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233164   

TargetAtaxin-1(Homo sapiens (Human))
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50233164(CHEMBL4105201 | US11124490, Compound 29)
Affinity DataIC50:  100nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50233164(CHEMBL4105201 | US11124490, Compound 29)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed