BDBM50233185 CHEMBL4090985::US11124490, Compound 25

SMILES Fc1cc(NC(=O)c2cc(NN3CCOCC3)c(Cl)cc2Cl)cc(F)c1F

InChI Key InChIKey=MAWJQZYKGLQWMB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233185   

TargetAtaxin-1(Homo sapiens (Human))
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50233185(CHEMBL4090985 | US11124490, Compound 25)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50233185(CHEMBL4090985 | US11124490, Compound 25)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed