BDBM50233188 CHEMBL4098521::US11124490, Compound 3i

SMILES COC(=O)c1c(F)cc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N2CCOCC2)cc1F

InChI Key InChIKey=JYZDMBCSWZPKJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233188   

TargetAtaxin-1(Homo sapiens (Human))
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50233188(CHEMBL4098521 | US11124490, Compound 3i)
Affinity DataIC50:  864nMAssay Description:Compound 3b was found to be the most potent ATX inhibitor with an IC50 of about 9 nM. The mechanism of action was determined to be competitive; howev...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50233188(CHEMBL4098521 | US11124490, Compound 3i)
Affinity DataIC50:  864nMAssay Description:Inhibition of recombinant human C-terminal FLAg-tagged ATX lysophospholipase D activity expressed in baculovirus infected sf9 cells using FRET based ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed