BDBM50233403 CHEMBL4062547

SMILES OB(O)c1ccccc1NC(=O)c1ccc(Oc2ccc(cn2)C(F)(F)F)cc1

InChI Key InChIKey=RRQHXCKMSAEUIP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50233403   

TargetHormone-sensitive lipase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50233403(CHEMBL4062547)
Affinity DataIC50:  91nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50233403(CHEMBL4062547)
Affinity DataIC50:  91nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 insect cells using PNPB as substrate after 5 mins by spectrophotometric ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50233403(CHEMBL4062547)
Affinity DataIC50:  470nMAssay Description:Inhibition of HSL in rat adipocytes assessed as reduction in lipolysis by measuring glycerol concentration incubated for 30 mins by spectrophotometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed