BDBM50234233 CHEMBL3094164

SMILES CN(C)CCCC1(OCc2cc(ccc12)-c1ccc(N)cc1)c1ccc(F)cc1

InChI Key InChIKey=HBJSMFYRIUQMKB-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234233   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
3D-2Drug

Curated by ChEMBL
LigandPNGBDBM50234233(CHEMBL3094164)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-(+/-)-citalopram from Sprague-Dawley rat brain SERT primary site (S1) after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
3D-2Drug

Curated by ChEMBL
LigandPNGBDBM50234233(CHEMBL3094164)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat brain stem SERT site S1 by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
3D-2Drug

Curated by ChEMBL
LigandPNGBDBM50234233(CHEMBL3094164)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of [3H]-S-citalopram dissociation from human SERT allosteric modulator site (S2) expressed in African green monkey COS7 cell membranes aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
3D-2Drug

Curated by ChEMBL
LigandPNGBDBM50234233(CHEMBL3094164)
Affinity DataIC50:  3.60E+3nMAssay Description:Allosteric modulation at wild-type human SERT site S2 expressed in african green monkey COS7 cells assessed as inhibition of [3H]citalopram dissociat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed