BDBM50236278 CHEMBL4077472

SMILES [H][C@@]12CO[C@@]([H])([C@H](O)[C@@H](O)[C@@H]1O)N2C(=S)NCCCCNC(=O)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

InChI Key InChIKey=MDCKIUURCNVTTJ-ZMHPAJMFSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50236278   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi:  300nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi:  2.08E+4nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase(Coffea arabica (Coffee beans))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236278(CHEMBL4077472)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of green coffee bean alpha-galactosidase using beta-D-glycopyranoside after 10 to 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed