BDBM50236279 CHEMBL4093241

SMILES [H][C@@]12CO[C@@]([H])([C@H](O)[C@@H](O)[C@@H]1O)N2C(=S)NCCCCCCCCCNC(=O)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

InChI Key InChIKey=YJLFXJUZBBBSCB-LHKMKVQPSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50236279   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236279(CHEMBL4093241)
Affinity DataKi:  600nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 in presence of bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236279(CHEMBL4093241)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 7 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236279(CHEMBL4093241)
Affinity DataKi:  7.20E+3nMAssay Description:In vitro inhibitory activity against human whole blood Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Sevilla

Curated by ChEMBL
LigandPNGBDBM50236279(CHEMBL4093241)
Affinity DataKi:  3.26E+4nMAssay Description:Inhibition of human GCase assessed as formation of 4-methylumbelliferone from 4-methylumbelliferyl alpha-D-glucopyranoside at pH 5 by luminescence sp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed