BDBM50236284 CHEMBL4069255

SMILES Cl.CC1(C)N=C(N)N=C(N)N1OCCCOc1ccc(cc1)C(=O)\C=C\c1ccccc1

InChI Key InChIKey=MHEOYLCWFYMVET-NTEUORMPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50236284   

TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50236284(CHEMBL4069255)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 30 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50236284(CHEMBL4069255)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of recombinant human DHFR assessed as reduction in conversion of DHF to THF measured every 30 secs for 6 mins by UV-Vis spectrophotometric...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50236284(CHEMBL4069255)
Affinity DataIC50:  3.24E+4nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 60 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed