BDBM50236514 CHEMBL4100504

SMILES C[C@H]1CCc2cc(ccc2N1C(=O)c1ccc(O)cc1O)-c1nc(Cl)ncc1C

InChI Key InChIKey=MZYFUTAKZNZIFC-ZDUSSCGKSA-N

Data  2 KI  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50236514   

LigandPNGBDBM50236514(CHEMBL4100504)
Affinity DataKi:  37nMAssay Description:Inhibition of fluorescein-labelled VER160364 binding to PDHK1 (unknown origin) after 90 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50236514(CHEMBL4100504)
Affinity DataKi:  1.98E+3nMAssay Description:Displacement of fluorescein-labelled VER160364 from HSP90A (unknown origin) after 90 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50236514(CHEMBL4100504)
Affinity DataIC50:  63nMAssay Description:Inhibition of PDHK1 (unknown origin) assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50236514(CHEMBL4100504)
Affinity DataKd:  19nMAssay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50236514(CHEMBL4100504)
Affinity DataKd:  19nMAssay Description:Binding affinity to PDHK1 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50236514(CHEMBL4100504)
Affinity DataIC50:  2.74E+3nMAssay Description:Binding affinity towards human Dopamine receptor D2 (long) by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed