BDBM50236939 CHEMBL2333945

SMILES Fc1ccc(cc1Cl)S(=O)(=O)NCc1ccc(cc1)C(=O)NNC(=O)c1ccccc1

InChI Key InChIKey=FYIBXBFDXNPBSF-UHFFFAOYSA-N

Data  12 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50236939   

Target1,3-beta-glucan synthase(Candida glabrata)
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50:  109nMAssay Description:Negative allosteric modulation of eGFP-fused human GluN2A receptor expressed in HEK293T cells assessed as inhibition of NMDA-induced channel current ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50:  512nMAssay Description:Antagonist activity at rat GluN1A/GluN2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced channel cur...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of human GluN2C receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50:  340nMAssay Description:Negative allosteric modulation of human GluN2A receptor expressed in HEK cells assessed as reduction in 3 uM glycine/glutamate-induced intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of human GluN2B receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50:  170nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2A expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50:  5.00E+4nMAssay Description:Negative allosteric modulation of human GluN2B receptor expressed in HEK cells assessed as reduction in glycine/glutamate-induced intracellular calci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50:  446nMAssay Description:Negative allosteric modulation of human GluN1/GluN2A receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced chann...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of human GluN2D receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50: >3.00E+4nMAssay Description:Negative allosteric modulation of human GluN2D receptor expressed in HEK cells assessed as reduction in glycine/glutamate-induced intracellular calci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50:  110nMAssay Description:Negative allosteric modulation of human GluN2A receptor expressed in HEK cells assessed as reduction in glycine/glutamate-induced intracellular calci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50:  320nMAssay Description:Negative allosteric modulation of human GluN2A receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed