BDBM50237998 CHEMBL1881960

SMILES Oc1nc2cc(Cl)c(Cl)cc2o1

InChI Key InChIKey=WLWRBOFZMOBYJR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50237998   

TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50237998(CHEMBL1881960)
Affinity DataIC50:  2.00E+3nMAssay Description:Compound was tested for binding affinity towards Opioid receptor mu 1 by displacing [3H]DAGO radioligand in rat brain P2 synaptosomes membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50237998(CHEMBL1881960)
Affinity DataIC50:  6nMAssay Description:Displacement of from norepinephrine transporter of frozen rat caudate membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Pseudomonas fluorescens)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50237998(CHEMBL1881960)
Affinity DataIC50:  500nMAssay Description:Displacement of [125I]RTI-55 from serotonin transporter of frozen rat caudate membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50237998(CHEMBL1881960)
Affinity DataIC50:  6.30nMAssay Description:Compound was tested for opioid receptor delta 1 agonism or antagonism in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed