BDBM50238584 CHEMBL4089797

SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@H](CO)NC(=O)[C@H](CCCSC)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H]2CSSC[C@H](NC(=O)CN)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N2

InChI Key InChIKey=UKHIGXYNOLBFDN-SNWZINOJSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50238584   

TargetNicotinic acetylcholine receptor alpha9/alpha10(RAT)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50238584(CHEMBL4089797)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at rat alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4(Rattus norvegicus (Rat))
Hainan University

Curated by ChEMBL
LigandPNGBDBM50238584(CHEMBL4089797)
Affinity DataIC50:  178nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
Hainan University

Curated by ChEMBL
LigandPNGBDBM50238584(CHEMBL4089797)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at rat alpha3beta2 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Rattus norvegicus (Rat))
Hainan University

Curated by ChEMBL
LigandPNGBDBM50238584(CHEMBL4089797)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at rat alpha2beta2 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Hainan University

Curated by ChEMBL
LigandPNGBDBM50238584(CHEMBL4089797)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at rat alpha7 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Hainan University

Curated by ChEMBL
LigandPNGBDBM50238584(CHEMBL4089797)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at rat alpha4beta2 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Hainan University

Curated by ChEMBL
LigandPNGBDBM50238584(CHEMBL4089797)
Affinity DataIC50:  3.90nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(MOUSE)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50238584(CHEMBL4089797)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-4(Rattus norvegicus (Rat))
Hainan University

Curated by ChEMBL
LigandPNGBDBM50238584(CHEMBL4089797)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at rat alpha2beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Rattus norvegicus (Rat))
Hainan University

Curated by ChEMBL
LigandPNGBDBM50238584(CHEMBL4089797)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at rat alpha4beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed