BDBM50239284 CHEMBL4096360

SMILES C(CNc1ncnc2cc(OCC3CCN(CCNc4ccnc5ccccc45)CC3)ccc12)Cc1ccccc1

InChI Key InChIKey=DPNGRMNVFKZZSM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239284   

TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Cnrs-Pierre Fabre Usr3388

Curated by ChEMBL
LigandPNGBDBM50239284(CHEMBL4096360)
Affinity DataEC50:  4.60E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Homo sapiens (Human))
Cnrs-Pierre Fabre Usr3388

Curated by ChEMBL
LigandPNGBDBM50239284(CHEMBL4096360)
Affinity DataEC50:  4.40E+3nMAssay Description:Inhibition of human DNMT3A catalytic domain using AdoMet assessed as reduction of methylation in 5'-biotin/3' 6-carboxyfluorescein labeled DNA duplex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed