BDBM50239287 CHEMBL4100095
SMILES C(CNc1ncnc2cc(OCC3CCN(CCNc4ccnc5ccccc45)CC3)ccc12)Nc1ccccc1
InChI Key InChIKey=IOFQDXBHAKWMAD-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50239287
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Cnrs-Pierre Fabre Usr3388
Curated by ChEMBL
Cnrs-Pierre Fabre Usr3388
Curated by ChEMBL
Affinity DataEC50: 7.30E+4nMAssay Description:Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA dup...More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 3A(Homo sapiens (Human))
Cnrs-Pierre Fabre Usr3388
Curated by ChEMBL
Cnrs-Pierre Fabre Usr3388
Curated by ChEMBL
Affinity DataEC50: 6.80E+3nMAssay Description:Inhibition of human DNMT3A catalytic domain using AdoMet assessed as reduction of methylation in 5'-biotin/3' 6-carboxyfluorescein labeled DNA duplex...More data for this Ligand-Target Pair