BDBM50240293 CHEMBL4073293

SMILES Cc1cnc(NS(=O)(=O)c2cc(Cl)c(NCC34CCCN3CCC4)cc2F)s1

InChI Key InChIKey=RNQZZJGFWUFCFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240293   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Department of Discovery Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50240293(CHEMBL4073293)
Affinity DataIC50:  2.42E+4nMAssay Description:Inhibition of 50% inactivated human Nav1.5alpha expressed in HEK293 cells at holding potential of -60 mV incubated for 5 mins measured at 10 secs int...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Department of Discovery Chemistry Merck

Curated by ChEMBL
LigandPNGBDBM50240293(CHEMBL4073293)
Affinity DataIC50:  142nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells at holding potential of -60 mV incubated for 5 mins measured at 10 secs int...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed