BDBM50240693 CHEMBL4097569
SMILES Cc1cnc(cc1Cc1ccc(cc1)-c1cscn1)C(=O)N[C@H]1CCOC[C@@H]1O
InChI Key InChIKey=VVZZHFMLRHJXTO-RXVVDRJESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50240693
Affinity DataKi: 19nMAssay Description:Displacement of [3H]PT-1284 human muscarinic acetylcholine receptor M1 expressed in CHO cell membranes after 90 mins scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: >4.00E+3nMAssay Description:Agonist activity at human muscarinic acetylcholine receptor M1 expressed in CHO cells assessed as increase in calcium mobilization incubated for 10 m...More data for this Ligand-Target Pair
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 4.94E+3nMAssay Description:Inhibition of PDE11A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Positive allosteric modulation of human muscarinic M1 receptor stably expressed in CHO cells assessed as increase in Ach-induced intracellular calciu...More data for this Ligand-Target Pair
Affinity DataEC50: 3.90E+3nMAssay Description:Partial agonist activity at muscarinic M1 receptor (unknown origin) assessed as recruitment of beta-arrestin by Path Hunter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 365nMAssay Description:Positive allosteric modulation of muscarinic M1 receptor (unknown origin) assessed as increase in Ach-induced recruitment of beta-arrestin by Path Hu...More data for this Ligand-Target Pair
Affinity DataEC50: 447nMAssay Description:Positive allosteric modulation of muscarinic M1 receptor (unknown origin) expressed in CHO cells assessed as increase in Ach-induced accumulation of ...More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Positive allosteric modulation of human muscarinic acetylcholine receptor M1 expressed in CHO cells assessed as increase in acetylcholine-induced cal...More data for this Ligand-Target Pair
Affinity DataIC50: 3.09E+3nMAssay Description:Inhibition of PDE2A (unknown origin)More data for this Ligand-Target Pair