BDBM50240721 (E)-(2S,3R)-2-Dimethylamino-octadec-4-ene-1,3-diol::CHEMBL322333::N,N-Dimethylsphingosine::N,N-dimethylspingosine::dimethylspingosine

SMILES CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](CO)N(C)C

InChI Key InChIKey=YRXOQXUDKDCXME-YIVRLKKSSA-N

Data  6 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240721   

TargetSphingosine kinase 2(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50240721((E)-(2S,3R)-2-Dimethylamino-octadec-4-ene-1,3-diol...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of His-tagged full length human recombinant SPHK2 expressed in baculovirus infected fall armyworm Sf9 cell expression system using sphingo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50240721((E)-(2S,3R)-2-Dimethylamino-octadec-4-ene-1,3-diol...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of His-tagged full length human recombinant SPHK1 expressed in baculovirus infected fall armyworm Sf9 cell expression system using sphingo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50240721((E)-(2S,3R)-2-Dimethylamino-octadec-4-ene-1,3-diol...)
Affinity DataIC50:  5.06E+4nMAssay Description:Inhibition of GST-tagged full length human recombinant SPHK1 expressed in baculovirus using sphingosine as substrate preincubated for 10 mins measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50240721((E)-(2S,3R)-2-Dimethylamino-octadec-4-ene-1,3-diol...)
Affinity DataIC50:  2.63E+4nMAssay Description:Inhibition of GST-tagged full length human recombinant SPHK2 expressed in baculovirus using sphingosine as substrate preincubated for 10 mins measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed