BDBM50243075 4-methyl-N3-(pyridin-3-yl)-N1-(3-(trifluoromethyl)phenyl)isophthalamide::CHEMBL469883

SMILES Cc1ccc(cc1C(=O)Nc1cccnc1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=RAKQGQRMHIXLRO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243075   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50243075(4-methyl-N3-(pyridin-3-yl)-N1-(3-(trifluoromethyl)...)
Affinity DataIC50:  294nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243075(4-methyl-N3-(pyridin-3-yl)-N1-(3-(trifluoromethyl)...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50243075(4-methyl-N3-(pyridin-3-yl)-N1-(3-(trifluoromethyl)...)
Affinity DataIC50:  18nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50243075(4-methyl-N3-(pyridin-3-yl)-N1-(3-(trifluoromethyl)...)
Affinity DataIC50:  219nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed