BDBM50243332 1-(5-(4-(2-(diethylamino)ethoxy)phenyl)-3-((3-(hydroxymethyl)phenyl)carbamoyl)thiophen-2-yl)urea::CHEMBL452020

SMILES CCN(CC)CCOc1ccc(cc1)-c1cc(C(=O)Nc2cccc(CO)c2)c(NC(N)=O)s1

InChI Key InChIKey=KDAJOEXXPZUAOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243332   

TargetCyclin-dependent kinase 2-associated protein 1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243332(1-(5-(4-(2-(diethylamino)ethoxy)phenyl)-3-((3-(hyd...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Cdk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243332(1-(5-(4-(2-(diethylamino)ethoxy)phenyl)-3-((3-(hyd...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed