BDBM50243849 7-(3-Chloro-4-fluorophenyl)-4,5,5-trimethyl-1,3,4,5-tetrahydro-H-1,4-benzodiazepin-2-one::CHEMBL486433

SMILES CN1CC(=O)Nc2ccc(cc2C1(C)C)-c1ccc(F)c(Cl)c1

InChI Key InChIKey=ZWTQESPCWJXBNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50243849   

TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243849(7-(3-Chloro-4-fluorophenyl)-4,5,5-trimethyl-1,3,4,...)
Affinity DataIC50:  105nMAssay Description:Inhibition of progesterone receptor mediated progesterone-induced alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed