BDBM50244566 (2R,3S)-2,3-dihydroxy-4-(naphthalen-2-ylsulfonyl)-N-((R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl)butanamide::CHEMBL453339

SMILES O[C@H](CS(=O)(=O)c1ccc2ccccc2c1)[C@@H](O)C(=O)N[C@@H]1CCCc2cc(CN3CCCCC3)ccc12

InChI Key InChIKey=XENUKVRWXVFLTR-MPFGFTFXSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50244566   

TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50244566((2R,3S)-2,3-dihydroxy-4-(naphthalen-2-ylsulfonyl)-...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in clone CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50244566((2R,3S)-2,3-dihydroxy-4-(naphthalen-2-ylsulfonyl)-...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in clone CHO-D-/aequorin cells by aquerin based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Oryctolagus cuniculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50244566((2R,3S)-2,3-dihydroxy-4-(naphthalen-2-ylsulfonyl)-...)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at rabbit bradykinin B1 receptor expressed in clone CHO-D-/aequorin cells by aquerin based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed