BDBM50246600 2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenylsulfonamido)acetic acid::CHEMBL515083

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(O)=O)CC(=O)NO

InChI Key InChIKey=QVAVQQVTOJMLHH-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50246600   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50:  322nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50:  1.69E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50:  6.77E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50:  193nMAssay Description:Inhibition of human recombinant MMP2 transfected in mouse melanoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElastase(Pseudomonas aeruginosa)
Uit - The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50:  1.69E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa pseudolysin using Abz-Ala-Gly-Leu-Ala-p-nitrobenzylamide as substrate after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50:  996nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Fibrogen

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50:  3.45E+5nMAssay Description:Inhibition of PCP after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMeprin A subunit beta(Homo sapiens)
Fraunhofer Institute For Cell Therapy and Immunology Izi

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50:  5.98E+3nMAssay Description:Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElastase(Pseudomonas aeruginosa)
Uit - The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50:  1.53E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa pseudolysin using Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(Dnp)-OH as substrate after 1 hr by fluorescence assay...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246600(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-methoxyphenyl...)
Affinity DataIC50:  213nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed