BDBM50247369 CHEMBL454922::N-butyl-1-(2-chloro-2-phenylethyl)-6-(propylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

SMILES CCCCNc1nc(SCCC)nc2n(CC(Cl)c3ccccc3)ncc12

InChI Key InChIKey=SWKWLDOGKJDBAI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50247369   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50247369(CHEMBL454922 | N-butyl-1-(2-chloro-2-phenylethyl)-...)
Affinity DataKi:  520nMAssay Description:Inhibition of human recombinant Abl by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50247369(CHEMBL454922 | N-butyl-1-(2-chloro-2-phenylethyl)-...)
Affinity DataKi:  525nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50247369(CHEMBL454922 | N-butyl-1-(2-chloro-2-phenylethyl)-...)
Affinity DataKi:  2.56E+3nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50247369(CHEMBL454922 | N-butyl-1-(2-chloro-2-phenylethyl)-...)
Affinity DataKi:  2.57E+3nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed