BDBM50249236 (R)-1-(4,9-dihydroxy-12-((R)-2-((4-hydroxyphenoxy)carbonyloxy)propyl)-2,6,7,11-tetramethoxy-3,10-dioxo-3,10-dihydroperylen-1-yl)propan-2-yl benzoate::CHEMBL460433

SMILES COc1cc(=O)c2c(O)c(OC)c(C[C@@H](C)OC(=O)Oc3ccc(O)cc3)c3c4c(C[C@@H](C)OC(=O)c5ccccc5)c(OC)c(O)c5c4c(c(OC)cc5=O)c1c23

InChI Key InChIKey=LSUTUUOITDQYNO-NHCUHLMSSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50249236   

TargetTranscription factor 7-like 2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50249236((R)-1-(4,9-dihydroxy-12-((R)-2-((4-hydroxyphenoxy)...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50249236((R)-1-(4,9-dihydroxy-12-((R)-2-((4-hydroxyphenoxy)...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50249236((R)-1-(4,9-dihydroxy-12-((R)-2-((4-hydroxyphenoxy)...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50249236((R)-1-(4,9-dihydroxy-12-((R)-2-((4-hydroxyphenoxy)...)
Affinity DataIC50:  7.70E+4nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50249236((R)-1-(4,9-dihydroxy-12-((R)-2-((4-hydroxyphenoxy)...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein-labeled human E-cadherin (residues 819-873) interaction by FP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50249236((R)-1-(4,9-dihydroxy-12-((R)-2-((4-hydroxyphenoxy)...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein-labeled human APC-R3 (residues 1477-1519) interaction by FP co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed