BDBM50249649 CHEMBL490121::Dimethyl-(8-phenyl-2,3,5,6-tetrahydro-1H,4H-13-selena-3a-aza-benzo[de]naphthacen-11-ylidene)-ammonium hexafluoro phosphate

SMILES C[N+](C)=c1ccc2c(-c3ccccc3)c3cc4CCCN5CCCc(c45)c3[se]c2c1

InChI Key InChIKey=OQGXCRJXQAJTPP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50249649   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50249649(CHEMBL490121 | Dimethyl-(8-phenyl-2,3,5,6-tetrahyd...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of verapamil-stimulated ATPase activity of human histidine10-tagged MDR1 expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50249649(CHEMBL490121 | Dimethyl-(8-phenyl-2,3,5,6-tetrahyd...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of human MDR1 expressed in MDCK2 cells assessed as enhancement of Calcein-AM uptake treated 30 mins before Calcein-AM challenge measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Mus musculus (Mouse))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50249649(CHEMBL490121 | Dimethyl-(8-phenyl-2,3,5,6-tetrahyd...)
Affinity DataIC50:  280nMAssay Description:Inhibition of verapamil-stimulated ATPase activity of mouse cysteine-less MDR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed