BDBM50250099 (S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(pyridine-3-carbonylamino)heptylboronic acid::CHEMBL449493

SMILES OB(O)CCCCC[C@H](NC(=O)c1cccnc1)C(=O)Nc1cccc(c1)-c1ccccc1

InChI Key InChIKey=ABEDQOQTISCLFO-QHCPKHFHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50250099   

TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50250099((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(pyridine-3-car...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human recombinant HDAC1 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50250099((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(pyridine-3-car...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant HDAC6 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50250099((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(pyridine-3-car...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human recombinant HDAC8 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50250099((S)-7-(Biphenyl-3-ylamino)-7-oxo-6-(pyridine-3-car...)
Affinity DataIC50:  830nMAssay Description:Inhibition of human recombinant HDAC2 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed