BDBM50251840 CHEMBL481110::endo-4-((3-(4-(benzo[d]thiazol-2-yloxy)phenylamino)-8-aza-bicyclo[3.2.1]octan-8-yl)methyl)benzoic acid

SMILES OC(=O)c1ccc(CN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Oc3nc4ccccc4s3)cc2)cc1

InChI Key InChIKey=OPKSCFOGUKTIRK-NUNAXRQHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251840   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251840(CHEMBL481110 | endo-4-((3-(4-(benzo[d]thiazol-2-yl...)
Affinity DataIC50:  9nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251840(CHEMBL481110 | endo-4-((3-(4-(benzo[d]thiazol-2-yl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of LTA4 hydrolase in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed