BDBM50252367 1-[3-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl}sulfonyl)phenyl]pyrrolidin-3-ol::CHEMBL520096
SMILES C[C@@H]1CN(CCN1S(=O)(=O)c1cccc(c1)N1CCC(O)C1)c1ccc(F)cc1C(F)(F)F
InChI Key InChIKey=UYNLBQQMXURQEN-NNJIEVJOSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50252367
Affinity DataIC50: 10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cells by cell based assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of rat 11betaHSD1More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of C57BL/6 mouse 11betaHSD1 in presence of human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells by cell based assayMore data for this Ligand-Target Pair