BDBM50252369 CHEMBL479606::Methyl 1-[3-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl}sulfonyl)phenyl]pyrrolidine-3-carboxylate

SMILES COC(=O)C1CCN(C1)c1cccc(c1)S(=O)(=O)N1CCN(C[C@H]1C)c1ccc(F)cc1C(F)(F)F

InChI Key InChIKey=WIAOEHXPHMNOKO-TZHYSIJRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252369   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252369(CHEMBL479606 | Methyl 1-[3-({(2R)-4-[4-fluoro-2-(t...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cells by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252369(CHEMBL479606 | Methyl 1-[3-({(2R)-4-[4-fluoro-2-(t...)
Affinity DataIC50:  55nMAssay Description:Inhibition of C57BL/6 mouse 11betaHSD1 in presence of human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252369(CHEMBL479606 | Methyl 1-[3-({(2R)-4-[4-fluoro-2-(t...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed