BDBM50252622 CHEMBL4070389

SMILES OC(=O)c1cccc(NC(=O)CCNC(=O)CCNCc2ccc(c(Cl)c2)-c2ccccc2)c1

InChI Key InChIKey=NZDQDPKZQDWCOF-UHFFFAOYSA-N

Data  4 IC50  3 Kd

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50252622   

TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataIC50:  370nMAssay Description:Inhibition of CK2alpha (unknown origin) using RRRADDSDDDD as substrate after 40 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataKd:  320nMAssay Description:Binding affinity to human CK2alpha expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha/beta(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataKd:  310nMAssay Description:Displacement of [125I]RANTES from human CCR2 expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataIC50:  370nMAssay Description:Inhibition of human CK2alpha using RRRDDDSDDD peptide as substrate preincubated for 40 mins and measured after 70 mins in the presence of ATP by ADP ...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha/beta(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataIC50:  670nMAssay Description:Binding affinity to CK2alpha/beta (unknown origin) expressed in Escherichia coli BL21(DE3) by ITCMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataIC50:  370nMAssay Description:Inhibition of recombinant human CK2alpha (1 to 336 residues) expressed in Escherichia coli BL21 (DE3) using RRADDSDDDD as substrate incubated for 10 ...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataKd:  320nMAssay Description:Antagonist activity at human CCR2b expressed in human Chem1 cells assessed as inhibition of human recombinant CCL2 induced Ca2+ mobilization preincub...More data for this Ligand-Target Pair