BDBM50253704 5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide::CHEMBL459309

SMILES Cc1c(nn(c1-c1ccc(Br)s1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1

InChI Key InChIKey=VEWBFNJDWKCEPL-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50253704   

TargetCannabinoid receptor 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50253704(5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-...)
Affinity DataIC50:  895nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50253704(5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-...)
Affinity DataIC50:  35.8nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50253704(5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-...)
Affinity DataEC50:  400nMAssay Description:Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50253704(5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-...)
Affinity DataEC50:  2.32E+4nMAssay Description:Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50253704(5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-...)
Affinity DataEC50:  68.2nMAssay Description:Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed