BDBM50253705 CHEMBL461216::N-(Azepan-1-yl)-5-(5-bromothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

SMILES Cc1c(nn(c1-c1ccc(Br)s1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCCC1

InChI Key InChIKey=XKHUPGMHSOHXQD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50253705   

TargetCannabinoid receptor 1(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50253705(CHEMBL461216 | N-(Azepan-1-yl)-5-(5-bromothiophen-...)
Affinity DataIC50:  40.7nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50253705(CHEMBL461216 | N-(Azepan-1-yl)-5-(5-bromothiophen-...)
Affinity DataEC50:  64.9nMAssay Description:Antagonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of Eu-GTP bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50253705(CHEMBL461216 | N-(Azepan-1-yl)-5-(5-bromothiophen-...)
Affinity DataIC50:  705nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed