BDBM50253741 (S)-2-((S)-4-((R)-2-Acetamido-3-amino propan-(4-fluorophenyl)-propanoyl)-2-oxo-3-propylpiperazin-1-yl)-N-methyl-3-(naphthalen-2-yl)propanamide::CHEMBL453734

SMILES CCC[C@@H]1N(CCN([C@@H](Cc2ccc3ccccc3c2)C(=O)NC)C1=O)C(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)C(C)(C)N

InChI Key InChIKey=RDQOUEKWQGRDRJ-ULNSLHSMSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50253741   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253741((S)-2-((S)-4-((R)-2-Acetamido-3-amino propan-(4-fl...)
Affinity DataKi:  9nMAssay Description:Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253741((S)-2-((S)-4-((R)-2-Acetamido-3-amino propan-(4-fl...)
Affinity DataKi:  174nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253741((S)-2-((S)-4-((R)-2-Acetamido-3-amino propan-(4-fl...)
Affinity DataKi:  322nMAssay Description:Displacement of europium-labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253741((S)-2-((S)-4-((R)-2-Acetamido-3-amino propan-(4-fl...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253741((S)-2-((S)-4-((R)-2-Acetamido-3-amino propan-(4-fl...)
Affinity DataEC50:  145nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253741((S)-2-((S)-4-((R)-2-Acetamido-3-amino propan-(4-fl...)
Affinity DataEC50:  44nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed