BDBM50255173 CHEMBL4097937

SMILES NC(=O)c1cnc(N[C@H]2CCCNC2)c2cc(sc12)-c1cccs1

InChI Key InChIKey=HUOVTXKPBCLDHL-JTQLQIEISA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255173   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50255173(CHEMBL4097937)
Affinity DataEC50:  12nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of camptothecin-induced G2/M phase arrestMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed