BDBM50256731 2-(1-phenylethyl)-3-p-tolyl-2,3-dihydroquinazolin-4(1H)-one::CHEMBL473806::VU0092145

SMILES CC(C1Nc2ccccc2C(=O)N1c1ccc(C)cc1)c1ccccc1

InChI Key InChIKey=QZAOSZVJAXUJFE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50256731   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50256731(2-(1-phenylethyl)-3-p-tolyl-2,3-dihydroquinazolin-...)
Affinity DataEC50:  3.00E+3nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50256731(2-(1-phenylethyl)-3-p-tolyl-2,3-dihydroquinazolin-...)
Affinity DataEC50:  3.00E+3nMAssay Description:Activation of human mGluR4 expressed in CHO cells coexpressing Gqi5 protein assessed as potentiation of glutamate-induced responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed