BDBM50258018 2-(4-tert-butylphenyl)-4-(4-((2-methyl-1H-imidazol-4-yl)methyl)piperazin-1-yl)-1H-benzo[d]imidazole::CHEMBL494400

SMILES Cc1ncc(CN2CCN(CC2)c2cccc3[nH]c(nc23)-c2ccc(cc2)C(C)(C)C)[nH]1

InChI Key InChIKey=YZHWAWRQSQQTQX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50258018   

TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258018(2-(4-tert-butylphenyl)-4-(4-((2-methyl-1H-imidazol...)
Affinity DataIC50:  28nMAssay Description:Displacement of [125I]-(D-Trp6)-GnRH from rat GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258018(2-(4-tert-butylphenyl)-4-(4-((2-methyl-1H-imidazol...)
Affinity DataIC50:  44nMAssay Description:Antagonist activity at human recombinant GnRH receptor expressed in HEK293 cells assessed as reduction in (D-Trp6)-GnRH-stimulated IP production by w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258018(2-(4-tert-butylphenyl)-4-(4-((2-methyl-1H-imidazol...)
Affinity DataIC50:  7.5nMAssay Description:Displacement of [125I]-(D-Trp6)-GnRH from human GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed