BDBM50259222 2-tert-butyl-7-(2-chlorophenyl)-6-(4-chlorophenyl)-4-(4-fluorophenyl)pyrido[2,3-d]pyrimidine::CHEMBL512422

SMILES CC(C)(C)c1nc(-c2ccc(F)cc2)c2cc(-c3ccc(Cl)cc3)c(nc2n1)-c1ccccc1Cl

InChI Key InChIKey=DGBMTWHOODPTEF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259222   

TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259222(2-tert-butyl-7-(2-chlorophenyl)-6-(4-chlorophenyl)...)
Affinity DataIC50:  9.83E+3nMAssay Description:Binding affinity to human cannabinoid CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259222(2-tert-butyl-7-(2-chlorophenyl)-6-(4-chlorophenyl)...)
Affinity DataIC50:  0.630nMAssay Description:Inverse agonist activity at human cannabinoid CB1R expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed