BDBM50261000 CHEMBL4080357

SMILES CCN([C@@H](C)Cc1noc(n1)-c1ccc(F)cc1)C(=O)c1nc(C)ccc1-n1nccn1

InChI Key InChIKey=SSVVKBOEKJMVND-HNNXBMFYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50261000   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50261000(CHEMBL4080357)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50261000(CHEMBL4080357)
Affinity DataIC50:  41nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed